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The boron neutorn capture therapy (BNCT) status to go into the new era

Zhou Yongmao

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 4-13

Abstract:

The paper briefly interprets the obvious progress of the boron neutorncapture therapy (BNCT) in the new era.It includes the BNCT clinical positioning, the tumour recurrence exploring, the boron concentration quantifeddetecting, the targeting boron compound composing and the in hospitor neutron source irradintors settingBNCT.

Keywords： neutron capture therapy     clinical trial     tumour recurrence     boron concentration detect     targeting boroncompound     in hospital neutron irradiator    

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Studies on preparation of folate-targeted boron liposomes as potential delivery agents for neutron capture

Wang Zhihui,Qin Linxue,Liu Dong

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 78-81

Abstract: folate-targeted liposomes with high encapsulation efficiency is an effective targeted drug delivery agent for boronneutron capture therapy (BNCT).

Keywords： boron neutron capture therapy     liposomes     folate-targeted     encapsulation efficiency    

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Boron neutron capture therapy for glioblastoma of prospects and confused

Zhou Youxin,Sun Ting,Yang Weilian,Du Ziwei

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 82-84

Abstract:

Boron neutron capture therapy (BNCT) is a selective radiotherapy of damageClinical trails of BNCT were carried out in fifties to sixties of 20 century in developed countries,but it was limited because of the development of boron carrier and neutron source.This is a review of BNCT prospect on glioblastoma multiform.

Keywords： boron neutron capture therapy     glioblastoma multiform     glioma stem cells    

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Boron neutron capture therapy of gliomas and refractory pituitary adenomas: current status and future

Dai Congxin,Yao Yong,Wang Renzhi

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 96-99

Abstract:

Clinical study of boron neutron capture therapy (BNCT) for gliomas hasHowever, efficacy of BNCT for brain tumors is far from being perfect at present because of the lack ofselectivity of the boron carriers and the characteristics of malignant glioma.Moreover, BNCT may have a significant therapeutic effect on refractory pituitary adenomas which havepituitary adenomas with BNCT.

Keywords： boron neutron capture therapy     gliomas     refractory pituitary adenomas    

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Performance and characteristic of in-hospital neutron irradiator

Li Yiguo,Xia Pu,Peng Dan,Zou Shuyun,Wu Xiaobo,Zhang Jinhua,Zhang Zizhu,Gao Jijin,Wang Liyu,Fu Jinshu,Liu Tong,Zhou Yongmao

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 20-22

Abstract:

The design of in hospital neutron irradiator (IHNI) and its systems were

Keywords： in-hospital neutron irradiator(IHNI)     boron neutron capture therapy(BNCT)     inherent safety    

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Neutron capture therapy clinical development in the world

Zhang Zichu,Jin Congjun,Liu Kai,Zhang Guozhen,Yang Lijun

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 100-105

Abstract:

Boron neutron capture therapy (BNCT) method was applied to about oneIn this paper, the principle of BNCT, the development history and international BNCT clinical progressThe BNCT clinical treatment situation and evaluation in glioblastoma (GBM), malignant melanoma, recurrent

Keywords： BNCT     GBM     malignant melanoma     recurent head & neck cancer     metastatic liver cancer    

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The physics scheme design for In-Hospital Neutron Irradiator Mark 1 reactor loaded low enrichment fuel

Jiang Xinbiao,Zhang Wenshou,Gao Jijin,Li Yiguo,Zhou Yongmao

Strategic Study of CAE 2009, Volume 11, Issue 11,   Pages 17-21

Abstract:

The core physics properties of 30 kW In-Hospital Neutron Irradiator-Markbeen discovered in the paper and it will provide theoretic basis for reactor engineering design and neutronbeam design for Boron Neutron Capture Therapy in the future.

Keywords： IHNI-1 reactor     boron neutron capture therapy     reactivity    

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Preliminary characterization of radiation fields of IHNI-1 for BNCT

Chen Jun,Li Chunjuan,Song Mingzhe,Li Wei,Yao Shunhe,Diao Lijun,Yao Yanling,Zhang Zizhu,Gao Jijin,Zhang Yifan

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 106-112

Abstract:

The characteristic parameters of the neutron radiation fields producedby an in-hospital neutron irradiatior for boron neutron capture therapy(BNCT), such as neutron energyspectra, neutron flux density and neutron absorbed dose rate and their spatial distributions in freeimprove the energy resolution in epithermal energy range and the ability to discriminate different neutronThe preliminary results show that the neutron flux densities of the irradiators achieve the expected

Keywords： in-hospital neutron irradiatior for BNCT     neutron enengy spectrum     neutron flux density     absorbed doserate of neutron and γ ray    

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Experimental study on BPA uptake of glioma cell lines

Yang Lei,Wang Xiao,Sui Li,Kong Fuquan,Hao Xiaojuan,Zheng Jieying,Ma Nanru,Cui Suzhen,Liu Quanwei,Zhao Kui

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 85-90

Abstract: Boron concentration in the cells was measured induced couple plasma-atomic emission spectroscopy (ICP-AESC6 cells were pre-incubated for 24 h with different boron concentrations in growth medium.Then the mediums were changed to boron-free ones, and boron content was assessed after 1, 2, 3 h.content of the 10B in cells was increasing with the increasing concentration of BPA, and the boron

Keywords： boron neutron capture therapy     BPA     glioma cell line     ICP AES    

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PGNAA system preliminary design and measurement of IHNI

Zhang Zichu,Li Lihua,Gao Jijin,Fu Jinshu

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 28-32

Abstract: For both detector shielding part and the neutron beam shielding part, the inner layer was natural LiFpowder and the outer was lead.Then boron concentration measurement experiments using this system were

Keywords： BNCT     IHNI     PGNAA     boron concentration     shielding    

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Synthesis of boron modified CoMo/Al

Hui Shang, Chong Guo, Pengfei Ye, Wenhui Zhang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 5,   Pages 1088-1098 doi: 10.1007/s11705-020-1969-y

Abstract: metals and the support, therefore, in this research, the modified CoMo/ -Al O catalysts with various boronThe effects of preparing methods as well as boron amounts on the active phase, acidic properties and

Keywords： CoMo catalyst     boron modification     surface acidity     microwave heating     selective hydrodesulfurization    

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Improving hole transfer of boron nitride quantum dots modified PDI for efficient photodegradation

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11,   Pages 1718-1727 doi: 10.1007/s11705-023-2319-7

Abstract: Herein, an effective and robust photocatalyst perylene-3,4,9,10-tetracarboxylic diamide/boron nitride

Keywords： PDI     boron nitride     quantum dots     photocatalysis     hole transfer    

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Mechanical responses of pristine and defective hexagonal boron-nitride nanosheets: A molecular dynamics

Mohammad SALAVATI, Arvin MOJAHEDIN, Ali Hossein Nezhad SHIRAZI

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 3,   Pages 623-631 doi: 10.1007/s11709-020-0616-5

Abstract: dynamics (MD) simulation to investigate the mechanical characteristics and failure mechanism of hexagonal boron-nitride

Keywords： hexagonal boron-nitride     mechanical properties     crack     notch     point defects     molecular dynamics    

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Statistical analysis of recombination properties of the boron-oxygen defect in p-type Czochralski silicon

Nitin NAMPALLI,Tsun Hang FUNG,Stuart WENHAM,Brett HALLAM,Malcolm ABBOTT

Frontiers in Energy 2017, Volume 11, Issue 1,   Pages 4-22 doi: 10.1007/s11708-016-0442-6

Abstract: the application of lifetime spectroscopy to the study of carrier-induced degradation ascribed to the boron-oxygenThe results demonstrate that the capture cross section ratio associated with the donor level of the BO

Keywords： Czochralski silicon     boron-oxygen defect     injection dependent lifetime spectroscopy     goodness-of-fit     repeatability    

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Optimization design for the epithermal neutron duct of in-hospital neutron irradiator mark 1 reactor

Jiang Xinbiao,Zhu Yangni,Zhao Zhumin,Chen Lixin,Zhou Yongmao

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 33-37

Abstract: text-align: justify;">Optimization design for the moderation layer and reflection layer of the epithermal neutronduct at in-hospital neutron irradiator mark 1(IHNI-1) reactor is carried out by using MCNP in this papercompared with Al materials, and two moderation optimization schemes which can obtain intensive epithermal neutronFinally, based on the moderation layer and reflection layer optimization schemes, the neutron and gammaspace distribution of the epithermal neutron beam at exit of this duct are detailed calculated.

Keywords： IHNI-1 reactor     epithermal neutron beam     neutron flux density    

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Title Author Date Type Operation

The boron neutorn capture therapy (BNCT) status to go into the new era

Zhou Yongmao

Journal Article

Studies on preparation of folate-targeted boron liposomes as potential delivery agents for neutron capture

Wang Zhihui,Qin Linxue,Liu Dong

Journal Article

Boron neutron capture therapy for glioblastoma of prospects and confused

Zhou Youxin,Sun Ting,Yang Weilian,Du Ziwei

Journal Article

Boron neutron capture therapy of gliomas and refractory pituitary adenomas: current status and future

Dai Congxin,Yao Yong,Wang Renzhi

Journal Article

Performance and characteristic of in-hospital neutron irradiator

Li Yiguo,Xia Pu,Peng Dan,Zou Shuyun,Wu Xiaobo,Zhang Jinhua,Zhang Zizhu,Gao Jijin,Wang Liyu,Fu Jinshu,Liu Tong,Zhou Yongmao

Journal Article

Neutron capture therapy clinical development in the world

Zhang Zichu,Jin Congjun,Liu Kai,Zhang Guozhen,Yang Lijun

Journal Article

The physics scheme design for In-Hospital Neutron Irradiator Mark 1 reactor loaded low enrichment fuel

Jiang Xinbiao,Zhang Wenshou,Gao Jijin,Li Yiguo,Zhou Yongmao

Journal Article

Preliminary characterization of radiation fields of IHNI-1 for BNCT

Chen Jun,Li Chunjuan,Song Mingzhe,Li Wei,Yao Shunhe,Diao Lijun,Yao Yanling,Zhang Zizhu,Gao Jijin,Zhang Yifan

Journal Article

Experimental study on BPA uptake of glioma cell lines

Yang Lei,Wang Xiao,Sui Li,Kong Fuquan,Hao Xiaojuan,Zheng Jieying,Ma Nanru,Cui Suzhen,Liu Quanwei,Zhao Kui

Journal Article

PGNAA system preliminary design and measurement of IHNI

Zhang Zichu,Li Lihua,Gao Jijin,Fu Jinshu

Journal Article

Synthesis of boron modified CoMo/Al

Hui Shang, Chong Guo, Pengfei Ye, Wenhui Zhang

Journal Article

Improving hole transfer of boron nitride quantum dots modified PDI for efficient photodegradation

Journal Article

Mechanical responses of pristine and defective hexagonal boron-nitride nanosheets: A molecular dynamics

Mohammad SALAVATI, Arvin MOJAHEDIN, Ali Hossein Nezhad SHIRAZI

Journal Article

Statistical analysis of recombination properties of the boron-oxygen defect in p-type Czochralski silicon

Nitin NAMPALLI,Tsun Hang FUNG,Stuart WENHAM,Brett HALLAM,Malcolm ABBOTT

Journal Article

Optimization design for the epithermal neutron duct of in-hospital neutron irradiator mark 1 reactor

Jiang Xinbiao,Zhu Yangni,Zhao Zhumin,Chen Lixin,Zhou Yongmao

Journal Article